| Primary Identifier | MGI:1096359 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 13082 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables retinoic acid 4-hydroxylase activity. Involved in cellular response to retinoic acid and retinoic acid catabolic process. Acts upstream of or within anterior/posterior pattern specification; central nervous system development; and neural crest cell development. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; extraembryonic component; and sensory organ. Orthologous to human CYP26A1 (cytochrome P450 family 26 subfamily A member 1). PHENOTYPE: Homozygotes for targeted null mutations die during mid-late gestation and exhibit spina bifida, caudal agenesis, and abnormalities of the kidneys, urogenital tract, hindgut, cervical vertebrae, and rostral hindbrain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
