| Primary Identifier | MGI:1921357 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 74107 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Located in intercellular bridge and midbody. Is expressed in cerebral cortex ventricular layer; germ cell of testis; and ovary. Used to study Meckel syndrome. Human ortholog(s) of this gene implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly. Orthologous to human CEP55 (centrosomal protein 55). PHENOTYPE: Mice homozygous for a null allele exhibit impaired cytokinesis in neural progenitor cells with postnatal lethality, microcephaly, decreased weight, pallor, and abnormal kidneys. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
