| Primary Identifier | MGI:98659 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 21673 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA nucleotidylexotransferase activity. Acts upstream of or within DNA metabolic process. Predicted to be located in cytosol; euchromatin; and nuclear lumen. Predicted to be active in nucleus. Is expressed in bone marrow; ovary; submandibular gland; testis; and thymus. Orthologous to human DNTT (DNA nucleotidylexotransferase). PHENOTYPE: Homozygous inactivation of this gene results in lack of "N" nucleotide insertions at the junctions of immunoglobulin and T cell receptor V(D)J rearrangements. Forced expression of terminal deoxynucleotidyl transferase in fetal thymus leads to decreased gamma-delta T cell number. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
