Primary Identifier | MGI:1933177 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 83490 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; regulation of inflammatory response; and regulation of innate immune response. Located in cytosol and plasma membrane. Orthologous to human PIK3AP1 (phosphoinositide-3-kinase adaptor protein 1). PHENOTYPE: Mice homozygous for disruptions in this gene have abnormalities in B cell maturation. [provided by MGI curators] |