Primary Identifier | MGI:1914823 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 67573 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-lysine 6-oxidase activity. Predicted to be involved in collagen fibril organization. Located in extracellular region. Is expressed in several structures, including gut; male reproductive gland or organ; otic capsule; skeleton; and trachea. Orthologous to human LOXL4 (lysyl oxidase like 4). PHENOTYPE: Mice homozygous for a knock-out allele have normal lysyl oxidase enzyme activity in the heart and aorta tissues and show normal development of angiotensin II-induced thoracic and abdominal aortic aneurysms. [provided by MGI curators] |