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Protein Coding Gene : Got1 glutamic-oxaloacetic transaminase 1, soluble
Primary Identifier  MGI:95791 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  14718
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables L-aspartate:2-oxoglutarate aminotransferase activity and phosphatidylserine decarboxylase activity. Involved in gluconeogenesis and malate-aspartate shuttle. Acts upstream of or within several processes, including dicarboxylic acid metabolic process; fatty acid homeostasis; and glycerol biosynthetic process. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1).
  • synonyms:
  • glutamic-oxaloacetic transaminase 1, soluble,
  • MGI:2147593,
  • MGD-MRK-10215,
  • AI789014,
  • Got-1,
  • Got1,
  • MGD-MRK-10213,
  • expressed sequence AI789014,
  • cytosolic aspartate aminotransferase,
  • cAspAT
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

6 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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