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Protein Coding Gene : Slc25a28 solute carrier family 25, member 28
Primary Identifier  MGI:2180509 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  246696
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ferrous iron transmembrane transporter activity. Predicted to be involved in iron import into the mitochondrion. Located in mitochondrion. Is expressed in several structures, including genitourinary system; gut; immune system; liver; and lung. Orthologous to human SLC25A28 (solute carrier family 25 member 28).
PHENOTYPE: Homozygous knockout results in reduced male fertility and exacerbates reduction of liver regeneration of hepatocyte specific Slc25a37 KO. Whole-body or hepatocyte specific KO affects iron metabolism and oxidative phosphorylation in liver mitochondria. [provided by MGI curators]
  • synonyms:
  • MGI:1922911,
  • Mrs3/4,
  • solute carrier family 25, member 28,
  • RIKEN cDNA 2210403D18 gene,
  • 2210403D18Rik,
  • Slc25a28,
  • Mfrn2
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