Primary Identifier | MGI:2385095 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 226154 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of fibroblast proliferation; and tube morphogenesis. Located in cytoplasm. Is expressed in several structures, including 1st branchial arch mandibular component; adrenal gland; forelimb bud; future brain; and genitourinary system. Used to study urinary system disease. Orthologous to human LZTS2 (leucine zipper tumor suppressor 2). PHENOTYPE: Mice homozygous for a null mutation display defects in urinary tract development. [provided by MGI curators] |