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Protein Coding Gene : Elovl3 ELOVL fatty acid elongase 3
Primary Identifier  MGI:1195976 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  12686
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable fatty acid elongase activity. Involved in fatty acid biosynthetic process and positive regulation of cold-induced thermogenesis. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in brown fat; embryo; head; and skin. Orthologous to human ELOVL3 (ELOVL fatty acid elongase 3).
PHENOTYPE: Homozygous mutants have a sparse coat, hyperplastic pilosebaceous system, and abnormal hair lipid content with high levels of eicosenoic acid. Liver and brown adipose tissue functions are normal. [provided by MGI curators]
  • synonyms:
  • cold inducible glycoprotein 30,
  • Cig30,
  • ELOVL fatty acid elongase 3,
  • elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3,
  • CIN-2,
  • Elovl3
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1 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Gene --> Protein-Protein Interactions

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Phenotype

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Disease

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