Primary Identifier | MGI:3629945 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 751550 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; and sensory perception of sound. Orthologous to human MIR146B (microRNA 146b). PHENOTYPE: Mice homozygous for a conditional allele activated in T cells exhibit normal humoral response. However, in conjuction with an Mir146 contional allele, exhibit exaccerbated increases of germinal B and T follicular helper cells. [provided by MGI curators] |