| Primary Identifier | MGI:88586 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 13074 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables steroid 17-alpha-monooxygenase activity. Involved in androgen biosynthetic process. Acts upstream of or within glucocorticoid biosynthetic process. Located in axon and neuronal cell body. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including adrenal gland; gut; nervous system; reproductive system; and retina layer. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate cancer. Orthologous to human CYP17A1 (cytochrome P450 family 17 subfamily A member 1). PHENOTYPE: Homozygous null embryos display early embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
