| Primary Identifier | MGI:2151054 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 94219 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity and magnesium ion transmembrane transporter activity. Acts upstream of or within magnesium ion transport. Located in basolateral plasma membrane. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and retina. Human ortholog(s) of this gene implicated in renal hypomagnesemia 6. Orthologous to human CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2). PHENOTYPE: Constitutive homozygous knockout is embryonic lethal. Homozygous KO in kidney leads to reduced serum magnesium levels and lower blood pressure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
