| Primary Identifier | MGI:2178563 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 76952 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GMP 5'-nucleotidase activity. Involved in allantoin metabolic process; amide catabolic process; and purine nucleoside monophosphate catabolic process. Is active in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II). PHENOTYPE: Bone marrow cells with a nucleotide substitution allele used in a transplantation experiment following tamoxifen-induction produce NOTCH1-induced tumors that are resistant to 6-mercaptopurine chemotherapy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
