Primary Identifier | MGI:3645665 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 240669 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables voltage-gated monoatomic ion channel activity. Involved in ATP export; protein heterooligomerization; and sensory perception of taste. Located in basolateral plasma membrane. Is expressed in circumvallate papillae and forebrain. Orthologous to human CALHM3 (calcium homeostasis modulator 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired voltage-activated nonselective currents, avoidance of bitter and salty taste, and loss of preference for sweet and unami. [provided by MGI curators] |