Primary Identifier | MGI:2180003 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 170750 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Predicted to be involved in bradykinin catabolic process; negative regulation of programmed cell death; and proteolysis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human XPNPEP1 (X-prolyl aminopeptidase 1). PHENOTYPE: Mice homozygous for a gene trap allele exhibit pre and postnatal lethality, reduced male survival, growth retardation with decreased body weight, size and length, microcephaly and peptiduria. [provided by MGI curators] |