| Primary Identifier | MGI:109162 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 14732 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycerol-3-phosphate O-acyltransferase activity. Involved in triglyceride biosynthetic process. Acts upstream of or within several processes, including fatty acid homeostasis; glycerolipid metabolic process; and negative regulation of activation-induced cell death of T cells. Located in mitochondrion. Is active in mitochondrial outer membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human GPAM (glycerol-3-phosphate acyltransferase, mitochondrial). PHENOTYPE: Homozygous mutant mice weighed less than controls and showed reduced triacylglycerol levels in the liver and plasma. The glycerolipid fatty acid composition is also disrupted in mutant mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
