| Primary Identifier | MGI:2147658 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 226250 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Predicted to be involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including adipose tissue; genitourinary system; gut; hemolymphoid system gland; and nervous system. Orthologous to human AFAP1L2 (actin filament associated protein 1 like 2). PHENOTYPE: Mice homozygous for a null allele exhibit a thicker tracheal epithelium and a transient tracheal epithelial hyperplasia during airway repair after injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
