| Primary Identifier | MGI:97723 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 18946 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; lipoprotein lipase activity; and phospholipase A1 activity. Predicted to be involved in several processes, including cholesterol homeostasis; high-density lipoprotein particle remodeling; and triglyceride catabolic process. Predicted to be located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Orthologous to human PNLIPRP1 (pancreatic lipase related protein 1). PHENOTYPE: Mice homozygous for a knock-out allele show increased lipase activity in pancreatic juice and develop obesity associated with increased body fat mass, impaired glucose tolerance and insulin resistance, with these conditions exacerbated on a high-fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
