Primary Identifier | MGI:1918903 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 71653 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables kinesin binding activity. Involved in several processes, including endoplasmic reticulum polarization; positive regulation of neuron migration; and regulation of establishment of cell polarity. Acts upstream of or within regulation of neuron migration. Located in several cellular components, including axonal growth cone; perikaryon; and perinuclear region of cytoplasm. Part of microtubule associated complex. Is expressed in several structures, including gut; lower urinary tract; nervous system; respiratory system; and sensory organ. Orthologous to human SHTN1 (shootin 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal projection of the forebrain commissural axons and partial postnatal lethality. [provided by MGI curators] |