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Protein Coding Gene : Kcnk18 potassium channel, subfamily K, member 18
Primary Identifier  MGI:2685627 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  332396
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables calcium-activated potassium channel activity. Involved in potassium ion transport and regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation. Located in plasma membrane. Is expressed in gut; male reproductive gland or organ; and olfactory lobe. Human ortholog(s) of this gene implicated in migraine. Orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit altered potassium conductance and neuron electrophysiology. [provided by MGI curators]
  • synonyms:
  • Tresk,
  • LOC332396,
  • TWIK-related individual K+ channel,
  • Gm781,
  • gene model 781, (NCBI),
  • Kcnk18,
  • potassium channel, subfamily K, member 18,
  • Trik,
  • Tresk-2
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