Primary Identifier | MGI:1890396 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 64707 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and histone H3K9me2 methyltransferase activity. Involved in circadian rhythm; male meiotic nuclear division; and negative regulation of macromolecule biosynthetic process. Located in heterochromatin and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and limb. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase). PHENOTYPE: Less than 5% of mice either heterozygous or homozygous for a reporter/null allele develop late-onset B cell lymphomas. [provided by MGI curators] |