| Primary Identifier | MGI:1921436 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 74186 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within negative regulation of gene expression; positive regulation of fat cell differentiation; and regulation of lipid biosynthetic process. Located in extracellular region. Is expressed in several structures, including cerebral cortex mantle layer; embryo mesenchyme; floor plate; nose; and right atrium. Orthologous to human CCDC3 (coiled-coil domain containing 3). PHENOTYPE: Aging mice homozygous for a null allele are lean and show decreased epididymal and subcutaneous adipose tissue weight and adipocyte size, mild hyperglycemia, increased insulin sensitivity, reduced liver triglyceride levels and steatosis, and fewer inflammatory cells in epididymal fat tissue. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
