Primary Identifier | MGI:2387350 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 227580 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in neurotransmitter receptor localization to postsynaptic specialization membrane and postsynaptic density assembly. Acts upstream of or within regulation of synapse organization. Located in extracellular region. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic cleft. Is expressed in several structures, including adipose tissue; brain; cranial ganglion; genitourinary system; and hemolymphoid system. Orthologous to human C1QL3 (complement C1q like 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired coordination, hyperactivity, decreased anxiety-related response, impaired contextual conditioning behavior, impaired CPP, impaired conditioned taste aversion and reduced density of excitatory synapses. [provided by MGI curators] |