Primary Identifier | MGI:1918448 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71198 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein K63-linked deubiquitination. Is expressed in embryo. Orthologous to human OTUD1 (OTU deubiquitinase 1). PHENOTYPE: Mice homozygous for a null allele are more resistant to lethal HSV-1 and VSV infection, but are more susceptible to LPS stimulation. [provided by MGI curators] |