Primary Identifier | MGI:2441697 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241263 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme activator activity and transmembrane signaling receptor activity. Involved in several processes, including cognition; positive regulation of neurotransmitter secretion; and protein localization to plasma membrane. Located in membrane. Is active in postsynaptic density membrane. Is expressed in eye; male reproductive gland or organ; nervous system; and small intestine. Orthologous to human GPR158 (G protein-coupled receptor 158). PHENOTYPE: Mice homozygous for a knock-out allele exhibit antidepressant-like behaviors, reduced anxiety-related response and elevated AMPAR-signalling. [provided by MGI curators] |