| Primary Identifier | MGI:104913 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 11308 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein tyrosine kinase activator activity and signaling adaptor activity. Acts upstream of or within megakaryocyte development; plasma membrane bounded cell projection morphogenesis; and somitogenesis. Located in lamellipodium and neuron projection. Part of SCAR complex. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human ABI1 (abl interactor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit background sensitive embryonic lethality prior during organogenesis associated with about abnormal vasculogenesis and angiogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
