| Primary Identifier | MGI:2449929 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 215257 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity. Acts upstream of or within negative regulation of myoblast differentiation; negative regulation of myoblast fusion; and positive regulation of interleukin-6 production. Located in extracellular space. Orthologous to human IL36G (interleukin 36 gamma). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to HSV-2 infection, influenza A infection, and S. pneumoniae and K. pneumonia infection, and decreased susceptibility to induced colitis, with defects in cytokine levels and macrophage physiology in response to infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
