Primary Identifier | MGI:1333816 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 107733 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL41 (mitochondrial ribosomal protein L41). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic growth retardation, disorganized extraembryonic tissue, abnormal primitive streak formation and gastrulation, and complete embryonic lethality by E9.5. Mice homozygous for a transgenic gene disruption exhibit flattened pancake appearance at E9. [provided by MGI curators] |