| Primary Identifier | MGI:2385325 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 241274 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables phosphatidylcholine lysophospholipase A1 activity. Involved in phosphatidylcholine catabolic process. Located in endoplasmic reticulum membrane and lipid droplet. Is expressed in central nervous system; germ cell of testis; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human PNPLA7 (patatin like domain 7, lysophospholipase). PHENOTYPE: Mice homozygous for a null allele exhibit premature death, weight loss, kyphosis, thin muscle fibers, decreased subcutaneous and visceral adipose tissue, increased food intake, hyperactivity, increased oxygen consumption, decreased body temperature, and browned white adipose tissue morphology with altered choline metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
