Primary Identifier | MGI:1914372 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 67122 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chloroplast targeting sequence binding activity. Acts upstream of or within several processes, including angiogenesis; positive regulation of vascular endothelial cell proliferation; and somite rostral/caudal axis specification. Is expressed in several structures, including cardiovascular system; central nervous system; embryo mesenchyme; genitourinary system; and retina. Orthologous to human NRARP (NOTCH regulated ankyrin repeat protein). PHENOTYPE: Mice homozygous for a null allele exhibit delayed retinal vascularization due to increased vascular regression. Mice homozygous for a different knock-out allele exhibit vertebral and rib fusions. [provided by MGI curators] |