Primary Identifier | MGI:1096863 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 12496 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nucleoside diphosphate phosphatase activity and ribonucleoside triphosphate phosphatase activity. Acts upstream of or within G protein-coupled receptor signaling pathway; platelet activation; and purine ribonucleoside diphosphate catabolic process. Located in basement membrane and plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2). PHENOTYPE: Mice homozygous for a null allele display smaller circumvallate papilla size and reduced neural responses to taste stimuli. [provided by MGI curators] |