| Primary Identifier | MGI:107692 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14347 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-(1->3)-fucosyltransferase activity. Involved in several processes, including leukocyte migration involved in inflammatory response; lymphocyte migration into lymph node; and regulation of leukocyte migration. Acts upstream of or within CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; T cell migration; and leukocyte migration involved in immune response. Predicted to be located in trans-Golgi network. Orthologous to human FUT7 (fucosyltransferase 7). PHENOTYPE: Mice homozygous for disruptions in this gene are superficially normal. However, abnormalities are found in immune cell function and lymph node morphology. Redeuced tumor metastasis is also seen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
