| Primary Identifier | MGI:1354731 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 30839 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of mitotic nuclear division. Part of SCF ubiquitin ligase complex. Is expressed in central nervous system; embryo; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FBXW5 (F-box and WD repeat domain containing 5). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to myocardial ischemic injury. Male mice for a null allele exhibit normal fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
