Primary Identifier | MGI:1340905 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 14133 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including antigen binding activity; carbohydrate derivative binding activity; and pattern recognition receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; activation of immune response; and positive regulation of interleukin-8 production. Predicted to be located in plasma membrane. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in brain; embryo; liver; and spleen. PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal collagen antibody-induced arthritis. [provided by MGI curators] |