| Primary Identifier | MGI:1915089 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 67839 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Predicted to be involved in several processes, including establishment of mitotic spindle orientation; negative regulation of GTPase activity; and negative regulation of guanyl-nucleotide exchange factor activity. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in cell cortex. Predicted to colocalize with Golgi membrane and endoplasmic reticulum membrane. Is expressed in several structures, including aorta; genitourinary system; gut; integumental system; and nervous system. Orthologous to human GPSM1 (G protein signaling modulator 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a lean phenotype, reduced fat mass, increased food consumption, increased nocturnal energy expenditure and altered blood pressure control mechanisms; surprisingly, their basal behavior and gross brain morphology remain normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
