| Primary Identifier | MGI:2449923 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 353156 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Notch binding activity. Involved in vasculogenesis. Acts upstream of or within negative regulation of smooth muscle cell migration. Located in extracellular space. Is expressed in several structures, including cardiovascular system; early conceptus; embryo mesenchyme; genitourinary system; and retina. Orthologous to human EGFL7 (EGF like domain multiple 7). PHENOTYPE: Mice homozygous for a null allele exhibit some embryonic lethality with absent heartbeat and systemic edema, delayed vasculogenesis, decreased angiogenesis, abnormal adult vasculature, and low-level hypoxia. Mice homozygous for a null allele that does not disrupt Mirn126 expression are normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
