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ncRNA Gene : Mir126a microRNA 126a
Primary Identifier  MGI:2676811 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  387145
Mgi Type  miRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including cellular response to estrogen stimulus; hematopoietic stem cell differentiation; and long-term synaptic potentiation. Located in synapse. Is expressed in several structures, including cardiovascular system; genitourinary system; retina; spleen; and yolk sac blood vessel. Orthologous to human MIR126 (microRNA 126).
PHENOTYPE: Mice with a conditional knock-out in CD4+ T cells exhibit aggravated psoriasis-like dermatitis in response to imiquimod with increased Th1 and Th17 cell infiltration in spleen. [provided by MGI curators]
  • synonyms:
  • Mirn126,
  • mmu-mir-126,
  • Mir126a,
  • mmu-mir-126a,
  • microRNA 126,
  • microRNA 126a,
  • Mir126
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