| Primary Identifier | MGI:1914762 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 67512 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 1-acylglycerol-3-phosphate O-acyltransferase activity. Involved in triglyceride biosynthetic process. Located in endoplasmic reticulum. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and urinary system. Used to study congenital generalized lipodystrophy type 1. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to human AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit loss of white and brown adipose tissue, insulin resistance, and hepatic steatosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
