Primary Identifier | MGI:98446 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20933 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription coregulator activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; positive regulation of transcription elongation by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is expressed in embryo; tibialis anterior; and tongue. Orthologous to human MED22 (mediator complex subunit 22). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete preweaning lethality. [provided by MGI curators] |