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Protein Coding Gene : Wdr5 WD repeat domain 5
Primary Identifier  MGI:2155884 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  140858
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone H3K4 methyltransferase activity. Involved in regulation of cell cycle; regulation of cell division; and regulation of embryonic development. Acts upstream of or within peptidyl-lysine methylation; positive regulation of gluconeogenesis; and skeletal system development. Located in nucleus. Part of ATAC complex. Is expressed in several structures, including cerebral cortex; colon; genitourinary system; hemolymphoid system gland; and vault of skull. Orthologous to human WDR5 (WD repeat domain 5).
  • synonyms:
  • WD repeat domain 5,
  • AA960360,
  • expressed sequence AA408785,
  • expressed sequence AA960360,
  • MGI:1922060,
  • Big-3,
  • Bmp2-induced gene,
  • RIKEN cDNA 2410008O07 gene,
  • Wdr5,
  • MGI:2138815,
  • 2410008O07Rik,
  • MGI:2138759,
  • AA408785
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Features --> Cross References

Genome

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

17 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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