Primary Identifier | MGI:1341158 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 14134 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sialic acid binding activity. Predicted to be involved in complement activation, lectin pathway. Predicted to be located in plasma membrane. Predicted to be part of serine-type endopeptidase complex. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in bone marrow; embryo; liver; spleen; and thymus. Orthologous to several human genes including FCN1 (ficolin 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to Streptococcus pneumoniae infection. [provided by MGI curators] |