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Protein Coding Gene : Olfm1 olfactomedin 1

Primary Identifier  MGI:1860437 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  56177
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in neuronal signal transduction and regulation of axon extension. Located in several cellular components, including axonal growth cone; neuronal cell body; and synaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic density membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; peripheral nervous system ganglion; sensory organ; and tooth. Orthologous to human OLFM1 (olfactomedin 1).
PHENOTYPE: Mice homozygous for a null mutation display reduced cerebral infarction size in males, decreased body weight and defects in embryo implantation, mating activity and ovulation in females, and reduced female fertility most likely as a secondary effect of impaired olfaction. [provided by MGI curators]
  • synonyms:
  • MGI:2139410,
  • Noelin 1,
  • Olfm1,
  • Noelin 2,
  • Pancortin 1-4,
  • expressed sequence AW742568,
  • AW742568,
  • olfactomedin 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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1 Driver For