Primary Identifier | MGI:1860267 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 56086 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to act upstream of or within negative regulation of neuron apoptotic process. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; sensory organ; skin; and tooth. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to several human genes including SET (SET nuclear proto-oncogene). PHENOTYPE: Mice homozygous for a null mutation display complete lethality during organogenesis with reduced embryo size, cardiac edema and an open neural tube. [provided by MGI curators] |