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Protein Coding Gene : Pkn3 protein kinase N3
Primary Identifier  MGI:2388285 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  263803
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in epithelial cell migration and intracellular signal transduction. Predicted to be located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including genitourinary system; heart; respiratory system; submandibular gland; and vascular system. Orthologous to human PKN3 (protein kinase N3).
PHENOTYPE: Mice homozygous for a null mutation are viable, fertile and healthy. Mice with conditional loss of this gene and Pten in hematopoietic cells show a delay in leukemia development. [provided by MGI curators]
  • synonyms:
  • cDNA sequence BC034126,
  • Pkn3,
  • MGI:2139325,
  • protein kinase N3,
  • BC034126,
  • expressed sequence AW209115,
  • AW209115
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