| Primary Identifier | MGI:1261433 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13804 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA endonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Involved in negative regulation of TOR signaling and positive regulation of autophagy. Acts upstream of or within several processes, including apoptotic DNA fragmentation; in utero embryonic development; and response to tumor necrosis factor. Located in mitochondrion. Is expressed in several structures, including brown fat; gut; liver; male reproductive gland or organ; and respiratory system. Orthologous to human ENDOG (endonuclease G). PHENOTYPE: Homozygous null mice are viable and have no detectable abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
