Primary Identifier | MGI:2138953 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 98970 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chitin binding activity. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in brain; liver; renal cortex; spinal cord mantle layer; and thymus primordium. Orthologous to human FIBCD1 (fibrinogen C domain containing 1). PHENOTYPE: Homozygous null mice that are neutrophil-depleted show decreased susceptibility to invasive pulmonary aspergillosis, however protection is not seen in immune-competent mice and in bleomycin-induced lung injury. [provided by MGI curators] |