| Primary Identifier | MGI:1917592 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 96979 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within positive regulation of DNA-templated transcription and secretion. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and urinary system. Orthologous to human PTGES2 (prostaglandin E synthase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal basal prostaglandin E2 (PGE2) protein levels in the lactating mammary gland. Mice homozygous for a different knock-out allele exhibit increased sensitivity to IgE antigen-dependent passive cutaneous anaphylaxis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
