|  Help  |  About  |  Contact Us

Protein Coding Gene : Sh2d3c SH2 domain containing 3C

Primary Identifier  MGI:1351631 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  27387
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway and small GTPase-mediated signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in cytosol. Orthologous to human SH2D3C (SH2 domain containing 3C).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality with absence of gastric milk. Surviving mice exhibit abnormal olfactory bulb innervation, fewer gonadotrophin positive cells in the hypothalamus, and decreased testes size. [provided by MGI curators]
  • synonyms:
  • Chat,
  • Shep1,
  • SH2 domain containing 3C,
  • Cas/HEF1-associated signal transducer,
  • novel SH2-containing protein 3,
  • SH2-containing Eph receptor-binding protein 1,
  • Sh2d3c,
  • Nsp3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For