| Primary Identifier | MGI:1860103 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 56017 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables D-glucose binding activity; dehydroascorbic acid transmembrane transporter activity; and hexose transmembrane transporter activity. Involved in D-glucose transmembrane transport; dehydroascorbic acid transport; and fructose transmembrane transport. Acts upstream of or within insulin receptor signaling pathway and response to hypoxia. Located in plasma membrane. Is expressed in several structures, including adipose tissue; gut; liver; placenta; and spleen. Orthologous to human SLC2A8 (solute carrier family 2 member 8). PHENOTYPE: Homozygotes for one null allele show reduced spermatozoan ATP levels, mitochondrial membrane potential and sperm motility, and a slight deviation from the expected Mendelian frequency. Homozygotes for another null allele show increased hippocampus cell proliferation and cardiac P-wave duration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
