| Primary Identifier | MGI:1347002 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 26360 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Predicted to be involved in blood coagulation. Located in extracellular space. Is expressed in several structures, including brain; intraembryonic coelom; limb segment; meninges; and skeleton. Used to study dermatomyositis. Orthologous to human ANGPTL2 (angiopoietin like 2). PHENOTYPE: When fed a high-fat diet, mice homozygous for a knock-out allele show decreased weight gain, reduced adipocity, a lower respiratory quotient, reduced inflammation in adipose tissues, enhanced glucose tolerance, and increased insulin sensitivity in both skeletal muscle and liver relative to controls. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
